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VU0948578

Chemical Structure : VU0948578

CAS No.:

VU0948578 (VU 0948578)

Catalog No.: PC-22563Not For Human Use, Lab Use Only.

VU0948578 is a potent, selective inhibitor of WT, A934T, and G288S SLACK channel (KCNT1, KNa1.1) with IC50 of 0.70, 0.59, 0.71 µM respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VU0948578 is a potent, selective inhibitor of WT, A934T, and G288S SLACK channel (KCNT1, KNa1.1) with IC50 of 0.70, 0.59, 0.71 µM respectively.

Physicochemical Properties

M.Wt 479.56
Formula C26H30FN5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

8-(butyl(4-fluorobenzyl)amino)-1-(3-methoxybenzyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione

References

1. Alshaima'a M Qunies, et al. Molecules. 2024 May 22;29(11):2437.

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