Chemical Structure : VU534
CAS No.: 923509-20-0
Catalog No.: PC-20921Not For Human Use, Lab Use Only.
VU534 is a small molecule activator of N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) with EC50 of 0.3 uM, enhances efferocytosis by macrophages.
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|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
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VU534 is a small molecule activator of N-acyl-phosphatidylethanolamine hydrolyzing phospholipase D (NAPE-PLD) with EC50 of 0.3 uM, enhances efferocytosis by macrophages.
VU534 (10 uM) increases the NAPE-PLD activity of RAW264.7 macrophages.
VU534 enhances efferocytosis in a NAPE-PLD-dependent manner in bone-marrow derived macrophages (BMDM).
| M.Wt | 447.54 | |
| Formula | C21H22FN3O3S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(5,7-dimethylbenzo[d]thiazol-2-yl)-1-((4-fluorophenyl)sulfonyl)piperidine-4-carboxamide |
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1. Jonah E Zarrow, et al. bioRxiv. 2023 Feb 28;2023.01.25.525554.

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