Chemical Structure : VU590 dihydrochloride
CAS No.:
1783987-83-6
VU590 dihydrochloride
(VU-590, VU 590)
Catalog No. : PC-60570Not For Human Use, Lab Use Only.
VU590 is the first small-molecule inhibitor of renal outer medullary potassium channel (ROMK, Kir1.1) and Kir7.1 with IC50 of 294 nM for ROMK.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6057001
Biological Activity
VU590 is the first small-molecule inhibitor of renal outer medullary potassium channel (ROMK , Kir1.1) and Kir7.1 with IC50 of 294 nM for ROMK.
Physicochemical Properties
M.Wt
561.46
Formula
C24H32N4O7.2HCl
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
7,13-Bis[(4-nitrophenyl)methyl]-1,4,10-trioxa-7,13-diazacyclopentadecane dihydrochloride
References
1. Lewis LM, et al. Mol Pharmacol.
2. Bhave G, et al. Mol Pharmacol
3. McCloskey C, et al. EMBO Mol Med
4. Kharade SV, et al. Mol Pharmacol.
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