Chemical Structure : VU6007477
CAS No.: 2220141-46-6
Catalog No.: PC-35747Not For Human Use, Lab Use Only.
VU6007477 is a potent, selective, CNS penetrant M1 positive allosteric modulator (PAM) with EC50 of 230 nM, 93% ACh max with minimal M1 agonist activity.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $348 | In stock | |
| 10 mg | $548 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
Bulk size, bulk discount!
Welcome credit card payment!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
VU6007477 is a potent, selective, CNS penetrant M1 positive allosteric modulator (PAM) with EC50 of 230 nM, 93% ACh max with minimal M1 agonist activity.
VU6007477 displays high selectivity against M2-M5.
| M.Wt | 430.512 | |
| Formula | C24H26N6O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-methyl-4-((6-(1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)methyl)-N-(tetrahydro-2H-pyran-4-yl)-1H-pyrrolo[2,3-b]pyridine-6-carboxamide |
|
1. Engers JL, et al. ACS Med Chem Lett. 2018 Sep 4;9(9):917-922.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright