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Chemical Structure : VU 6008667
Catalog No.: PC-62118Not For Human Use, Lab Use Only.
VU 6008667 is a potent, highly selective M5 negative allosteric modulator with IC50 of 1.2 uM.
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VU 6008667 is a potent, highly selective M5 negative allosteric modulator with IC50 of 1.2 uM.
VU 6008667 shows high CNS penetration, excellent selectivity versus M1-4 and the desired short half-life (t1/2=2.3h) in rats.
| M.Wt | 438.859 | |
| Formula | C24H17ClF2N2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. McGowan KM, et al. Bioorg Med Chem Lett. 2017 Mar 15;27(6):1356-1359.
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