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VU6009003

Chemical Structure : VU6009003

CAS No.: 2135885-84-4

VU6009003 (VU 6009003)

Catalog No.: PC-63278Not For Human Use, Lab Use Only.

VU6009003 is a potent, selective, CNS penetrant mAChR M4 positive allosteric modulator with EC50 of 197 nM and 437 nM for human and rat M4, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    VU6009003 is a potent, selective, CNS penetrant mAChR M4 positive allosteric modulator with EC50 of 197 nM and 437 nM for human and rat M4, respectively.

    Physicochemical Properties

    M.Wt 358.445
    Formula C22H22N4O
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-methyl-4-(4-((6-methylpyridin-3-yl)oxy)piperidin-1-yl)quinoline-3-carbonitrile

    References

    1. Bewley BR, et al. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4274-4279.

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