VU6009003 |CAS:2135885-84-4 Probechem Biochemicals

Chemical Structure : VU6009003

VU6009003 (VU 6009003)

Catalog No.: PC-63278Not For Human Use, Lab Use Only.

VU6009003 is a potent, selective, CNS penetrant mAChR M4 positive allosteric modulator with EC50 of 197 nM and 437 nM for human and rat M4, respectively.

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Biological Activity

VU6009003 is a potent, selective, CNS penetrant mAChR M4 positive allosteric modulator with EC50 of 197 nM and 437 nM for human and rat M4, respectively.

Physicochemical Properties

M.Wt	358.445
Formula	C22H22N4O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6-methyl-4-(4-((6-methylpyridin-3-yl)oxy)piperidin-1-yl)quinoline-3-carbonitrile

References

1. Bewley BR, et al. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4274-4279.

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VU6009003 (VU 6009003)

Biological Activity

Physicochemical Properties

References

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