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VU6009048

Chemical Structure : VU6009048

CAS No.: 2226116-93-2

VU6009048 (VU 6009048)

Catalog No.: PC-38116Not For Human Use, Lab Use Only.

VU6009048 is a potent, selective M4 positive allosteric modulator (PAM) with EC50 of 85 nM (hM4) and 379 nM (rM4).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    VU6009048 is a potent, selective M4 positive allosteric modulator (PAM) with EC50 of 85 nM (hM4) and 379 nM (rM4).

    Physicochemical Properties

    M.Wt 283.393
    Formula C16H17N3S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-cyclobutyl-2,4-dimethylthieno[2,3-b:5,4-c']dipyridin-8-amine

    References

    1. Madeline F Long, et al. Bioorg Med Chem Lett. 2021 Dec 1;53:128416.

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