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Chemical Structure : VU6015241
Catalog No.: PC-72662Not For Human Use, Lab Use Only.
VU6015241 (VU 6015241) is a highly potent and selective antagonist of M4 muscarinic acetylcholine receptor (mAChR4) with IC50 of 71 nM.
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VU6015241 (VU 6015241) is a highly potent and selective antagonist of M4 muscarinic acetylcholine receptor (mAChR4) with IC50 of 71 nM.
VU6015241 demonstrates selectivity across multiple species, excellent aqueous solubility, and moderate brain exposure in rodents after intraperitoneal administration.
| M.Wt | 449.599 | |
| Formula | C26H35N5O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Aaron M Bender, et al. Bioorg Med Chem Lett. 2022 Jan 15;56:128479.
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