VU6080824 | Kir2.1 inhibitor | Probechem Biochemicals

Chemical Structure : VU6080824

VU6080824 (VU 6080824)

Catalog No.: PC-25574Not For Human Use, Lab Use Only.

VU6080824 is a potent, selective inhibitor of the inward-rectifier potassium channel Kir2.1 with IC50 of 5.9 uM in Kir2.1 thallium flux assays, selective relative to Kir1.1 and Kir4.1 up to 10 uM.

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Biological Activity

VU6080824 is a potent, selective inhibitor of the inward-rectifier potassium channel Kir2.1 with IC50 of 5.9 uM in Kir2.1 thallium flux assays, selective relative to Kir1.1 and Kir4.1 up to 10 uM.

Physicochemical Properties

M.Wt	333.43
Formula	C22H23NO2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(3'-Methoxy-[1,1'-biphenyl]-4-yl)-N-(4-methoxybenzyl)methanamine

References

1. Duncan RA, et al. ACS Med Chem Lett. 2025 Aug 29;16(9):1762-1771.

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VU6080824 (VU 6080824)

Biological Activity

Physicochemical Properties

References

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