VU625 | AeKir1 inhibitor | Probechem Biochemicals

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Chemical Structure : VU625

VU625 (VU0077625)

Catalog No.: PC-25403Not For Human Use, Lab Use Only.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

VU625 (VU0077625) is a potent and selective inhibitor of Aedes aegypti Kir1 (AeKir1) channel with IC50 of 96.8 nM in patch clamp electrophysiology experiments of HEK293 cells, selective for AeKir1 over mammalian Kir channels and AeKir2B channel.
VU625 inhibits AeKir1- and AeKir2B-mediated K+ currents with IC50 values of 3.8 µM and 45.1 µM respectively.

Physicochemical Properties

M.Wt	374.46
Formula	C19H22N2O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-methoxyphenyl)-2-methyl-1-propionylindoline-5-sulfonamide

References

1. Raphemot R, et al. PLoS One. 2014 Nov 6;9(11):e110772.

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VU625 (VU0077625)

Biological Activity

Physicochemical Properties

References

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