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Chemical Structure : VUF10460
CAS No.: 1028327-66-3
Catalog No.: PC-42380Not For Human Use, Lab Use Only.
VUF10460 is a potent, selective histamine H4 receptor agonist with pKi of 7.46 and 8.22 for rat and human H4, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $88 | In stock | |
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $358 | In stock | |
| 100 mg | Get quote |
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VUF10460 is a potent, selective histamine H4 receptor agonist with pKi of 7.46 and 8.22 for rat and human H4, respectively.
VUF10460 displays >50-fold selectivity over H3 receptors.
VUF10460 significantly enhances HCl-induced gastric lesions in rat stomach, but not the H3 selective agonist JNJ7777120.
| M.Wt | 269.34486 | |
| Formula | C15H19N5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 36 mg/mL |
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| Chemical Name/SMILES |
2-Pyrimidinamine, 4-(4-methyl-1-piperazinyl)-6-phenyl- |
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1. Coruzzi G, et al. Eur J Pharmacol. 2011 Nov 1;669(1-3):121-7.
2. Adami M, et al. Pharmacology. 2012;89(5-6):287-94.
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