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VX-150

Chemical Structure : VX-150

CAS No.: 1793080-72-4

VX-150 (VX150)

Catalog No.: PC-22573Not For Human Use, Lab Use Only.

VX-150 is a highly selective, orally bioavailable NaV1.8 channel inhibitor, shows >400-fold selectivity over other sodium channel subtypes, induces analgesia in a variety of evoked pain tests, without affecting subject safety.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

VX-150 is a highly selective, orally bioavailable NaV1.8 channel inhibitor, shows >400-fold selectivity over other sodium channel subtypes, induces analgesia in a variety of evoked pain tests, without affecting subject safety.

Physicochemical Properties

M.Wt 516.34
Formula C21H17F4N2O7P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4-(2-(4-Fluoro-2-methylphenoxy)-4-(trifluoromethyl)benzamido)-2-oxopyridin-1(2H)-yl)methyl dihydrogen phosphate

References

1. Hijma HJ, et al. Pain Med. 2021 Aug 6;22(8):1814-1826.

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