VX-710 | MDR modulator | Probechem Biochemicals

Chemical Structure : VX-710

VX-710 (Biricodar, VX710)

Catalog No.: PC-21826Not For Human Use, Lab Use Only.

Biricodar (VX-710) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), modulates Pgp, MRP-1, and BCRP(R482), enhances chemosensitivity in resistant cells.

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Biological Activity

Biricodar (VX-710) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), modulates Pgp, MRP-1, and BCRP(R482), enhances chemosensitivity in resistant cells.

Physicochemical Properties

M.Wt	603.72
Formula	C34H41N3O7
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1,7-dipyridin-3-ylheptan-4-yl (2S)-1-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate

References

1. Germann UA, et al. Anticancer Drugs. 1997 Feb;8(2):125-40.

2. Minderman H, et al. Clin Cancer Res. 2004 Mar 1;10(5):1826-34.

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VX-710 (Biricodar, VX710)

Biological Activity

Physicochemical Properties

References

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