VX-853 | MDR modulator | Probechem Biochemicals

Chemical Structure : VX-853

VX-853 (Timcodar, VX853)

Catalog No.: PC-21827Not For Human Use, Lab Use Only.

Timcodar (VX-853) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), directly blockes EtBr efflux in S. aureus.

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Biological Activity

Timcodar (VX-853) is small molecule modulator of P-glycoprotein (Pgp) and multidrug resistance protein (MRP-1), directly blockes EtBr efflux in S. aureus.

Physicochemical Properties

M.Wt	749.31
Formula	C43H45ClN4O6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S)-N-benzyl-3-(4-chlorophenyl)-N-(1,5-dipyridin-4-ylpentan-3-yl)-2-[methyl-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]amino]propanamide

References

1. Mullin S, et al. Antimicrob Agents Chemother. 2004 Nov;48(11):4171-6.

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VX-853 (Timcodar, VX853)

Biological Activity

Physicochemical Properties

References

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