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Chemical Structure : Valproic acid
CAS No.: 99-66-1
Catalog No.: PC-42670Not For Human Use, Lab Use Only.
Valproic acid is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 g | $48 | In stock | |
| 5 g | $88 | In stock | |
| 10 g | Get quote |
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Valproic acid (2-Propylpentanoic Acid) is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
Valproic acid induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from AML patients.
Valproic acid reduces tumor growth and metastasis formation in animal model.
| M.Wt | 144.2114 | |
| Formula | C8H16O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in H2O |
|
| Chemical Name/SMILES |
Pentanoic acid, 2-propyl- |
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1. Krämer OH, et al. EMBO J. 2003 Jul 1;22(13):3411-20.
2. Göttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.
3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.
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