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Chemical Structure : Valproic acid sodium salt
CAS No.: 1069-66-5
Catalog No.: PC-42671Not For Human Use, Lab Use Only.
Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 500 mg | $58 | In stock | |
| 1 g | $88 | In stock | |
| 5 g | Get quote |
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Valproic acid sodium salt is a HDAC inhibitor that selectively inhibits the catalytic activity of class I HDACs, and induces proteasomal degradation of HDAC2.
Valproic acid induces differentiation of carcinoma cells, transformed hematopoietic progenitor cells and leukemic blasts from AML patients.
Valproic acid reduces tumor growth and metastasis formation in animal model.
| M.Wt | 166.1933 | |
| Formula | C8H15NaO2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: ≥ 48 mg/mL |
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| Chemical Name/SMILES |
Pentanoic acid, 2-propyl-, sodium salt (1:1) |
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1. Krämer OH, et al. EMBO J. 2003 Jul 1;22(13):3411-20.
2. Göttlicher M, et al. EMBO J. 2001 Dec 17;20(24):6969-78.
3. Phiel CJ, et al. J Biol Chem. 2001 Sep 28;276(39):36734-41.
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