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Valspodar

Chemical Structure : Valspodar

CAS No.: 121584-18-7

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Valspodar (PSC833, SDZ PSC-833)

Catalog No.: PC-45207Not For Human Use, Lab Use Only.

Valspodar (PSC-833) is a highly potent multidrug-resistance modifier that acts as a P-glycoprotein MDR1 inhibitor, exhibits effectivity at preventing cancer cell resistance to chemotherapeutics.

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5 mg $358 In stock
10 mg $558 In stock
25 mg $898 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Valspodar (PSC-833) is a highly potent multidrug-resistance modifier that acts as a P-glycoprotein MDR1 inhibitor, exhibits effectivity at preventing cancer cell resistance to chemotherapeutics.

Physicochemical Properties

M.Wt 1214.622
Formula C63H111N11O12
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 12 mg/mL
Chemical Name/SMILES

Cyclosporin A, 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-

References

1. Boesch D, et al. Cancer Res. 1991 Aug 15;51(16):4226-33.

2. Ehrlich PH, et al. Anticancer Res. 1997 Jan-Feb;17(1A):129-33.

3. Hu XF, et al. Clin Cancer Res. 1996 Apr;2(4):713-20.

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