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Vapendavir

Chemical Structure : Vapendavir

CAS No.: 439085-51-5

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Vapendavir (BTA798, BTA-798)

Catalog No.: PC-63340Not For Human Use, Lab Use Only.

Vapendavir (BTA798) is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Vapendavir (BTA798) is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.
Vapendavir (BTA798) efficiently inhibits the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C.
Vapendavir (BTA798) is currently under clinical study for the treatment of rhinovirus infections.

Physicochemical Properties

M.Wt 382.464
Formula C21H26N4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-ethoxy-6-[2-[1-(6-methylpyridazin-3-yl)piperidin-4-yl]ethoxy]-1,2-benzoxazole

References

1. Tijsma A, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2.

2. Sun L, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.

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