Chemical Structure : Vapendavir diphosphate
CAS No.: 1198151-75-5
Catalog No.: PC-21970Not For Human Use, Lab Use Only.
Vapendavir (BTA798) diphosphate is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.
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Vapendavir (BTA798) diphosphate is a novel potent enteroviral capsid binder, inhibits EV71 replication of all isolates with mean EC50 of 0.7 uM.
Vapendavir (BTA798) efficiently inhibits the in vitro replication of 21 EV71 strains/isolates that are representative of the different genogroups A, B, and C.
Vapendavir (BTA798) is currently under clinical study for the treatment of rhinovirus infections.
M.Wt | 578.45 | |
Formula | C21H32N4O11P2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1,2-Benzisoxazole, 3-ethoxy-6-[2-[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy]-, phosphate (1:2) |
1. Tijsma A, et al. Antimicrob Agents Chemother. 2014 Nov;58(11):6990-2.
2. Sun L, et al. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5.
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