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Chemical Structure : Vedolizumab
CAS No.:
Catalog No.: PC-Ab1072Not For Human Use, Lab Use Only.
Vedolizumab (MLN-0002) is a humanized monoclonal antibody, which acts against α 4 β 7 integrin heterodimer and blocks the interaction of α4β7 integrin with mucosal address in cell adhesion molecule-1 (MAdCAM-1). Vedolizumab inhibits the migration of memory T-lymphocytes across the endothelium into inflamed gastrointestinal (GI) parenchymal tissue, impairs the migration of gut-homing lymphocytes into the mucosa, thereby acting as a gut-selective anti-lymphocyte-trafficking immunomodulator..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $358 | In stock | |
| 5 mg | $758 | In stock | |
| 10 mg | $1280 | In stock | |
| 100 mg | Get quote |
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Vedolizumab (MLN-0002) is a humanized monoclonal antibody, which acts against α 4 β 7 integrin heterodimer and blocks the interaction of α4β7 integrin with mucosal address in cell adhesion molecule-1 (MAdCAM-1). Vedolizumab inhibits the migration of memory T-lymphocytes across the endothelium into inflamed gastrointestinal (GI) parenchymal tissue, impairs the migration of gut-homing lymphocytes into the mucosa, thereby acting as a gut-selective anti-lymphocyte-trafficking immunomodulator.
| M.Wt | ||
| Formula | Human IgG1-Kappa | |
| Appearance | Solid | |
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| Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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