Verducatib (BI 1291583) | Cathepsin C inhibitor

Chemical Structure : Verducatib

CAS No.: 1887236-33-0

Verducatib (BI 1291583, BI1291583, BI-1291583)

Catalog No.: PC-24193Not For Human Use, Lab Use Only.

Verducatib (BI 1291583) is a potent, selective, reversible inhibitor of cathepsin C (CatC, DPP-1) with IC50 of 1.1 nM, patent WO2016038007 A1 (compound II).

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5 mg	$478	In stock
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Biological Activity

Verducatib (BI 1291583) is a potent, selective, reversible inhibitor of cathepsin C (CatC, DPP-1) with IC50 of 1.1 nM, patent WO2016038007 A1 (compound II).

Physicochemical Properties

M.Wt	530.64
Formula	C31H35FN4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(1R,3S,4S)-N-((S)-1-cyano-2-(2-fluoro-4-(1'-(oxetan-3-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-6-yl)phenyl)ethyl)-2-azabicyclo[2.2.1]heptane-3-carboxamide

References

1. Patent WO2016038007 A1 (compound II).

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Verducatib (BI 1291583, BI1291583, BI-1291583)

Biological Activity

Physicochemical Properties

References

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