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Verducatib

Chemical Structure : Verducatib

CAS No.: 1887236-33-0

Verducatib

Catalog No.: PC-24193Not For Human Use, Lab Use Only.

Verducatib is a potent, selective inhibitor of cathepsin C (CatC) with IC50 of 1.1 nM, patent WO2016038007 A1 (compound II).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Verducatib is a potent, selective inhibitor of cathepsin C (CatC) with IC50 of 1.1 nM, patent WO2016038007 A1 (compound II).

Physicochemical Properties

M.Wt 530.64
Formula C31H35FN4O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(1R,3S,4S)-N-((S)-1-cyano-2-(2-fluoro-4-(1'-(oxetan-3-yl)-3H-spiro[isobenzofuran-1,4'-piperidin]-6-yl)phenyl)ethyl)-2-azabicyclo[2.2.1]heptane-3-carboxamide

References

1. Patent WO2016038007 A1 (compound II).

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