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Chemical Structure : Verinurad
CAS No.: 1352792-74-5
Catalog No.: PC-45065Not For Human Use, Lab Use Only.
Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with IC50 of 25 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $148 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | $428 | In stock | |
| 250 mg | Get quote |
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Verinurad (RDEA3170) is a highly potent and specific URAT1 inhibitor with IC50 of 25 nM.
Verinurad (RDEA3170) displays 200-fold lower affinity for the related URAT1 homologs OAT4 and OAT1.
Verinurad (RDEA3170) reduces the sUA by up to 60% with a single 40 mg dose in healthy human volunteers, and increases the FEUA in a dose-dependent manner with EC50 of 22 nM.
Verinurad (RDEA3170) shows pptential for the treatment of gout and asymptomatic hyperuricemia.
| M.Wt | 348.4182 | |
| Formula | C20H16N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Propanoic acid, 2-[[3-(4-cyano-1-naphthalenyl)-4-pyridinyl]thio]-2-methyl- |
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1. Tan PK, et al. Sci Rep. 2017 Apr 6;7(1):665.
2. Shen Z, et al. Drug Des Devel Ther. 2017 Jul 7;11:2077-2086.
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