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Vernakalant hydrochloride

Chemical Structure : Vernakalant hydrochloride

CAS No.: 748810-28-8

Vernakalant hydrochloride (RSD1235 hydrochloride)

Catalog No.: PC-23682Not For Human Use, Lab Use Only.

Vernakalant (RSD1235) is an atrial-selective antifibrillatory agent and mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker, inhibits wild-type and mutant Kv1.5 channels.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Vernakalant (RSD1235) is an atrial-selective antifibrillatory agent and mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker, inhibits wild-type and mutant Kv1.5 channels.

Physicochemical Properties

M.Wt 385.93
Formula C20H32ClNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-1-((1R,2R)-2-(3,4-Dimethoxyphenethoxy)cyclohexyl)pyrrolidin-3-ol hydrochloride

References

1. Dorian P, et al. J Cardiovasc Pharmacol. 2007 Jul;50(1):35-40.

2. Eldstrom J, et al. Mol Pharmacol. 2007 Dec;72(6):1522-34.

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