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Chemical Structure : Verosudil
CAS No.: 1414854-42-4
Catalog No.: PC-62715Not For Human Use, Lab Use Only.
Verosudil (AR-12286) is a potent ROCK inhibitor with Ki of 2 nM for both ROCK1 and ROCK2.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $238 | In stock | |
| 10 mg | $388 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Verosudil (AR-12286) is a potent ROCK inhibitor with Ki of 2 nM for both ROCK1 and ROCK2.
Verosudil (AR-12286) effectively lowers intraocular pressure (IOP) primarily by increasing aqueous humour outflow through the trabecular meshwork in animal models.
| M.Wt | 327.402 | |
| Formula | C17H17N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(dimethylamino)-N-(1-oxo- 1,2-dihydroisoquinolin-6-yl)-2-(thiophen-3-yl)acetamide |
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1. Sturdivant JM, et al. Bioorg Med Chem Lett. 2016 May 15;26(10):2475-80.
2. Kopczynski C, et al. Br J Ophthalmol. 2013 May;97(5):567-72.
3. Williams RD, et al. Am J Ophthalmol. 2011 Nov;152(5):834-41.e1.
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