Chemical Structure : Verteporfin
CAS No.: 129497-78-5
Catalog No.: PC-36118Not For Human Use, Lab Use Only.
Verteporfin (CL 318952, BPD-MA) is a benzoporphyrin derivative that inhibits Yap via disruption of YAP-TEAD interactions, Verteporfin is a clinically used photosensitizer.
Packing | Price | Stock | Quantity |
---|---|---|---|
5 mg | $128 | In stock | |
10 mg | $198 | In stock | |
25 mg | $328 | In stock | |
50 mg | $498 | In stock | |
100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Verteporfin (CL 318952, BPD-MA) is a benzoporphyrin derivative that inhibits Yap via disruption of YAP-TEAD interactions, Verteporfin is a clinically used photosensitizer.
Verteporfin inhibits growth of hepatoma cells without photoactivation through inhibition of YAP-TEAD complex.
Verteporfin inhibited tumor cell proliferation and restored sensitivity to cisplatin in urothelial cell carcinoma (UCC).
Verteporfin blocks tumor growth of uveal melanoma cells containing Gq/11 mutations.
M.Wt | 718.8 | |
Formula | C41H42N4O8 | |
Appearance | Solid | |
Storage |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
(4R,4aS)-rel-18-ethenyl-4,4a-dihydro-3,4-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoic acid, monomethyl ester |
1. Brodowska K, et al. Exp Eye Res. 2014 Jul;124:67-73.
2. Yu FX, et al. Cancer Cell. 2014 Jun 16;25(6):822-30.
3. Perra A, et al. J Hepatol. 2014 Nov;61(5):1088-96.
4. Ciamporcero E, et al. Oncogene. 2016 Mar 24;35(12):1541-53.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright