Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Vestipitant
Catalog No.: PC-61578Not For Human Use, Lab Use Only.
Vestipitant (GW597599) is a potent, selective, orally active NK1 receptor antagonist with pKi of 9.65.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Vestipitant (GW597599) is a potent, selective, orally active NK1 receptor antagonist with pKi of 9.65.
Vestipitant (GW597599) potently blocks Substance P-mediated phosphorylation of ERK.
Vestipitant (GW597599) attenuates fear-induced foot-tapping in gerbils, separation-induced distress-vocalizations in guinea pigs, marble-burying behaviour in mice, and displayes anxiolytic actions in rats.
| M.Wt | 491.454 | |
| Formula | C23H24F7N3O | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Di Fabio R, et al. J Med Chem. 2009 May 28;52(10):3238-47.
2. Brocco M, et al. Eur Neuropsychopharmacol. 2008 Oct;18(10):729-50.
3. Ratti E, et al. Sleep. 2013 Dec 1;36(12):1823-30.
4. Poma SZ, et al. J Psychopharmacol. 2014 May;28(5):491-7.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
