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Vibozilimod

Chemical Structure : Vibozilimod

CAS No.: 1403232-33-6

Vibozilimod (SCD-044, SCD 044)

Catalog No.: PC-38427Not For Human Use, Lab Use Only.

Vibozilimod (SCD 044) is an orally-available, potent, selective sphingosine-1-phosphate receptor-1 (S1PR1) agonist with EC50 of 0.2 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Vibozilimod (SCD 044) is an orally-available, potent, selective sphingosine-1-phosphate receptor-1 (S1PR1) agonist with EC50 of 0.2 nM.
Vibozilimod (SCD 044) displays high selectivity for S1PR1 over S1PR2 and S1PR3, which can be associated with serious side effects.
Vibozilimod (SCD 044) demonstrated potential synergy with other mechanisms in IBD- like IL-23 blockade.

Physicochemical Properties

M.Wt 542.073
Formula C29H36ClN3O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-(5-(3-chloro-4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)benzyl)-4-((2-methoxyethoxy)methyl)piperidine-4-carboxylic acid

References

1. Patent. WO2012140020A1.

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