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Vilaprisan

Chemical Structure : Vilaprisan

CAS No.: 1262108-14-4

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Vilaprisan (BAY 1002670;BAY 10-02670)

Catalog No.: PC-63436Not For Human Use, Lab Use Only.

Vilaprisan (BAY 1002670) is a highly potent and selective progesterone receptor (PR) modulator (SPRM).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Vilaprisan (BAY 1002670) is a highly potent and selective progesterone receptor (PR) modulator (SPRM).
    Vilaprisan exhibits marked efficacy in an innovative humanized fibroid disease model.
    Vilaprisan is a very promising treatment option for uterine fibroids.

    Physicochemical Properties

    M.Wt 544.577
    Formula C27H29F5O4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (8S,11R,13S,14S,17R)-17-hydroxy-13-methyl-11-(4-(methylsulfonyl)phenyl)-17-(perfluoroethyl)-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

    References

    1. Wagenfeld A, et al. Hum Reprod. 2013 Aug;28(8):2253-64.

    2. Schütt B, et al. Hum Reprod. 2016 Aug;31(8):1703-12.

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