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Vinblastine sulfate

Chemical Structure : Vinblastine sulfate

CAS No.: 143-67-9

Vinblastine sulfate

Catalog No.: PC-22871Not For Human Use, Lab Use Only.

Vinblastine sulfate is a cytotoxic alkaloid that binds tubulin and inhibits the assembly of microtubules, a chemotherapy agent for treatment of a number of types of cancer.

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Biological Activity

Vinblastine sulfate is a cytotoxic alkaloid that binds tubulin and inhibits the assembly of microtubules, a chemotherapy agent for treatment of a number of types of cancer.

Physicochemical Properties

M.Wt 909.06
Formula C46H60N4O13S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methyl (3aR,3a1R,4R,5S,5aR,10bR)-4-acetoxy-3a-ethyl-9-((5S,9S)-5-ethyl-5-hydroxy-9-(methoxycarbonyl)-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methano[1]azacycloundecino[5,4-b]indol-9-yl)-5-hydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate sulfate

References

1. McKay DB, et al. Proc Soc Exp Biol Med. 1993 Jul;203(3):372-6.

2. Bánóczi Z, et al. Bioconjug Chem. 2010 Nov 17;21(11):1948-55.

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