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Virstatin

Chemical Structure : Virstatin

CAS No.: 88909-96-0

Virstatin

Catalog No.: PC-22958Not For Human Use, Lab Use Only.

Virstatin is a small-molecule inhibitor of transcription factor ToxT, inhibits the pili system synthesis and prevents A. baumannii biofilm formation, reduces virulence in vitro.

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Biological Activity

Virstatin is a small-molecule inhibitor of transcription factor ToxT, inhibits the pili system synthesis and prevents A. baumannii biofilm formation, reduces virulence in vitro.

Physicochemical Properties

M.Wt 283.28
Formula C16H13NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)butanoic acid

References

1. Markham LE, et al. ACS Med Chem Lett. 2021 Aug 24;12(9):1493-1497.

2. Woodbrey AK, et al. Biochemistry. 2018 Sep 25;57(38):5609-5615.

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