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Chemical Structure : Vorasidenib
CAS No.: 1644545-52-7
Catalog No.: PC-60534Not For Human Use, Lab Use Only.
Vorasidenib (AG-881) is a potent, oral, brain-penetrant dual inhibitor of mIDH1 and mIDH2 with IC50 of 6 nM and 12 nM for IDH1-R132H and IDH2-R140Q, respectively.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $498 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
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| M.Wt | 414.74 | |
| Formula | C14H13ClF6N6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
6-(6-chloropyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine |
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1. Konteatis Z, et al. ACS Med Chem Lett. 2020 Jan 22;11(2):101-107.
2. Mellinghoff IK, et al. N Engl J Med. 2023 Aug 17;389(7):589-601.
3. Mellinghoff IK, et al. Nat Med. 2023 Mar;29(3):615-622.
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