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Voriconazole

Chemical Structure : Voriconazole

CAS No.: 137234-62-9

Voriconazole (UK-109496;UK109496;UK 109496)

Catalog No.: PC-45964Not For Human Use, Lab Use Only.

Voriconazole (UK109496) is a triazole antifungal agent that acts as a 14α-demethylase inhibitor.

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Biological Activity

Voriconazole (UK109496) is a triazole antifungal agent that acts as a 14α-demethylase inhibitor.
Voriconazole is used to treat and prevent invasive fungal infections including aspergillosis andcandidiasis and fungal infections caused by Scedosporium and Fusarium species.

Physicochemical Properties

M.Wt 349.3105
Formula C16H14F3N5O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-Pyrimidineethanol, α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, (αR,βS)-

References

1. Patterson TF, et al. Clin Infect Dis. 2016 Aug 15;63(4):e1-e60.

2. Herbrecht R, et al. N Engl J Med. 2002 Aug 8;347(6):408-15.

3. Smith J, et al. Antimicrob Agents Chemother. 2006 Apr;50(4):1570-2.

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