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WAY-213613 hydrochloride

Chemical Structure : WAY-213613 hydrochloride

CAS No.: 2450268-84-3

WAY-213613 hydrochloride (WAY213613 hydrochloride)

Catalog No.: PC-28282Not For Human Use, Lab Use Only.

WAY-213613 hydrochloride (WAY213613) is a potent, non-substrate inhibitor of EAAT2 (GLT-1) with IC50 of 85 nM, displays > 44-fold selectivity over EAAT1 and EAAT3.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

WAY-213613 hydrochloride (WAY213613) is a potent, non-substrate inhibitor of EAAT2 (GLT-1) with IC50 of 85 nM, displays > 44-fold selectivity over EAAT1 and EAAT3.
WAY-213613 also exhibits no activity towards ionotropic and metabotropic glutamate receptors.

Physicochemical Properties

M.Wt 451.65
Formula C16H14BrClF2N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[4-(2-Bromo-4,5-difluorophenoxy)phenyl]-L-asparagine hydrochloride

References

1. Dunlop J, et al. Mol Pharmacol. 2005 Oct;68(4):974-82.

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