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Chemical Structure : WAY-262611
CAS No.: 1123231-07-1
Catalog No.: PC-42795Not For Human Use, Lab Use Only.
WAY-262611 (WAY262611) is a potent, orally active and Wnt/β-catenin pathway agonist with EC50 of 0.63 nM, via inhibition of dickkopf-1 (DKK-1).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $188 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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WAY-262611 (WAY262611) is a potent, orally active and Wnt/β-catenin pathway agonist with EC50 of 0.63 nM, via inhibition of dickkopf-1 (DKK-1).
WAY-262611 increases bone formation rate in ovariectomized rats.
WAY-262611 inhibits cell migration of fibroblast-like synoviocytes (FLSs) in rheumatoid arthritis.
| M.Wt | 318.4155 | |
| Formula | C20H22N4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 42 mg/mL |
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| Chemical Name/SMILES |
4-Piperidinemethanamine, 1-[4-(2-naphthalenyl)-2-pyrimidinyl]- |
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1. Pelletier JC, et al. J Med Chem. 2009 Nov 26;52(22):6962-5.
2. Enochson L, et al. Osteoarthritis Cartilage. 2014 Apr;22(4):566-77.
3. Choe JY, et al. Rheumatology (Oxford). 2016 May;55(5):928-38.
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