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Chemical Structure : WAY-267464
Catalog No.: PC-35701Not For Human Use, Lab Use Only.
WAY-267464 (WAY267464) is a potent, selective, non-peptide oxytocin receptor agonist with Ki of 58.4 nM, >100-fold selectivity over V1a, V2, V1b receptors.
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WAY-267464 (WAY267464) is a potent, selective, non-peptide oxytocin receptor agonist with Ki of 58.4 nM, >100-fold selectivity over V1a, V2, V1b receptors.
WAY-267464 exhibits an anxiolytic-like profile similar to oxytocin (OT), also significantly reverses disruption in prepulse inhibition of the acoustic startle reflex induced by either MK-801 or amphetamine in vivo.
| M.Wt | 654.593 | |
| Formula | C32H37Cl2N7O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Ring RH, et al. Neuropharmacology. 2010 Jan;58(1):69-77.
2. Hicks C, et al. J Neuroendocrinol. 2012 Jul;24(7):1012-29.
3. Hicks C, et al. Br J Pharmacol. 2014 Jun;171(11):2868-87.
4. Hicks C, et al. Psychopharmacology (Berl). 2015 Aug;232(15):2659-67.
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