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You are here:Home-Chemical Inhibitors & Agonists-Wnt/Notch/Hedgehog-sFRP-1-WAY 316606
WAY 316606

Chemical Structure : WAY 316606

CAS No.: 915759-45-4

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WAY 316606 (WAY-316606;WAY316606)

Catalog No.: PC-42718Not For Human Use, Lab Use Only.

WAY 316606 (WAY-316606, WAY316606) is a small molecule inhibitor of the secreted protein sFRP-1 with IC50 of 0.5 uM in FP binding assay.

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5 mg $88 In stock
10 mg $128 In stock
25 mg $198 In stock
50 mg $328 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

WAY 316606 (WAY-316606, WAY316606) is a small molecule inhibitor of the secreted protein sFRP-1 with IC50 of 0.5 uM in FP binding assay.
WAY 316606 exhibits Wnt signaling inhibition in U2-OS cell lines with EC50 of 0.65 uM.

Physicochemical Properties

M.Wt 448.4797
Formula C18H19F3N2O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzenesulfonamide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoromethyl)-

References

1. Moore WJ, et al. J Med Chem. 2009 Jan 8;52(1):105-16.

2. Bodine PV, et al. Bone. 2009 Jun;44(6):1063-8.

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