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WEE1/CK1α degrader 1

Chemical Structure : WEE1/CK1α degrader 1

CAS No.:

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WEE1/CK1α degrader 1

Catalog No.: PC-22392Not For Human Use, Lab Use Only.

WEE1/CK1α degrader 1 is a highly potent WEE1/CK1α molecular glue degrader with DC50 of 1.1/3.1 nM, respectively.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

WEE1/CK1α degrader 1 is a highly potent WEE1/CK1α molecular glue degrader with DC50 of 1.1/3.1 nM, respectively.

Physicochemical Properties

M.Wt 431.50
Formula C24H25N5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO
Chemical Name/SMILES

3-(5-(3-(tert-butylamino)imidazo[1,2-a]pyridin-2-yl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

References

1. Razumkov H, et al. bioRxiv [Preprint]. 2024 May 5:2024.05.04.592550.

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