WEE1Hu inhibitor 1 |CAS:2211167-11-0 Probechem Biochemicals

Chemical Structure : WEE1Hu inhibitor 1

WEE1Hu inhibitor 1 (Wee1A inhibitor 1)

Catalog No.: PC-35251Not For Human Use, Lab Use Only.

WEE1Hu inhibitor is a novel potent inhibitor of WEE1Hu kinase (also known as Wee1A) with IC50 of 68 nM against recombined WEE1Hu in ELISA assays.

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Biological Activity

WEE1Hu inhibitor 1 is a novel potent inhibitor of WEE1Hu kinase (also known as Wee1A) with IC50 of 68 nM against recombined WEE1Hu in ELISA assays.
WEE1Hu inhibitor 1 inhibits lung cancer cell Hep-3B and Huh-7 cell proliferation with IC50 of <1 uM and 10-100 uM, respectively.

Physicochemical Properties

M.Wt	461.311
Formula	C18H20IN7
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(1H-imidazol-1-yl)-5-iodo-N-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidin-2-amine

References

1. US Patent WO 2018056621.

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WEE1Hu inhibitor 1 (Wee1A inhibitor 1)

Biological Activity

Physicochemical Properties

References

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