WEE1 degrader 1

Chemical Structure : WEE1 degrader 1

Catalog No.: PC-22390Not For Human Use, Lab Use Only.

WEE1 degrader 1 is a potent, selective CRBN-dependent WEE1 molecular glue degrader with DC50 of 91 nM, does not degrade CK1α.

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Biological Activity

WEE1 degrader 1 is a potent, selective CRBN-dependent WEE1 molecular glue degrader with DC50 of 91 nM, does not degrade CK1α.

M.Wt	403.40
Formula	C21H17N5O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(5-(2-aminoimidazo[1,2-a]pyridine-3-carbonyl)-1-oxoisoindolin-2-yl)piperidine-2,6-dione

1. Razumkov H, et al. bioRxiv [Preprint]. 2024 May 5:2024.05.04.592550.