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Chemical Structure : WKYMVm hexapeptide
CAS No.: 187986-17-0
Catalog No.: PC-72084Not For Human Use, Lab Use Only.
WKYMVm hexapeptide is a potent, selective, pan-agonist for the formyl peptide receptors FPR1, FPR2 (EC50 = 75 pM) and FPR3 (EC50 = 3 nM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $258 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $598 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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WKYMVm hexapeptide is a potent, selective, pan-agonist for the formyl peptide receptors FPR1, FPR2 (EC50 = 75 pM) and FPR3 (EC50 = 3 nM).
WKYMVm induces Ca2+ mobilization and superoxide production in, and chemotaxic migration of, monocytes and neutrophils.
WKYMVm also promotes monocyte survival through a PKC-, PI3-kinase- and Akt-dependent pathway.
| M.Wt | 856.11 | |
| Formula | C41H61N9O7S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(S)-6-amino-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-N-((5S,8S,11S,14S)-5-carbamoyl-15-(4-hydroxyphenyl)-8-isopropyl-11-(2-(methylthio)ethyl)-7,10,13-trioxo-2-thia-6,9,12-triazapentadecan-14-yl)hexanamide |
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1. Francesca Wanda Rossi, et al. J Immunol. 2015 Jun 1;194(11):5161-73.
2. Park B, et al. J Cell Mol Med. 2021 Sep;25(18):8936-8946.
3. Hu J, et al. J Cell Mol Med. 2020 Jan;24(2):1893-1905.
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