Catalog No.: PC-20391Not For Human Use, Lab Use Only.
WRW4 (Trp-Arg-Trp-Trp-Trp-Trp) is a selective antagonist of formyl peptide receptor 2 (FPR2, FPRL1) signaling, inhibits WKYMVm binding to FPR2 with IC50 of 0.23 uM.
WRW4 (Trp-Arg-Trp-Trp-Trp-Trp) is a selective antagonist of formyl peptide receptor 2 (FPR2, FPRL1) signaling, inhibits WKYMVm binding to FPR2 with IC50 of 0.23 uM.
WRW4 inhibits intracellular calcium release induced by WKYMVm, MMK 1, amyloid β42, and F peptide.
WRW4 also inhibits FPR2-mediated signaling in human neutrophils.
WRW4 blocks chemotactic migration and superoxide generation by amyloid β42 peptide.
