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Chemical Structure : Wntepane 1
Catalog No.: PC-62039Not For Human Use, Lab Use Only.
Wntepane 1 is a small-molecule activator of the Wnt pathway that modulates the van-Gogh-like receptor 1 (Vangl1), activates Wnt signaling with EC50 of 1.8 uM in the reporter gene assay.
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Wntepane 1 is a small-molecule activator of the Wnt pathway that modulates the van-Gogh-like receptor 1 (Vangl1), activates Wnt signaling with EC50 of 1.8 uM in the reporter gene assay.
Wntepane 1 interacts with Vangl1 (and possibly Vangl2 as well) and thereby at least partially liberates and restores the signal transducing activity of Dsh.
Wntepane 1 is an advantageous tool for the study of biological processes mediated by Vangl1.
| M.Wt | 474.557 | |
| Formula | C28H30N2O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Basu S, et al. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6805-10.
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