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XF-73

Chemical Structure : XF-73

CAS No.: 718638-68-7

XF-73 (Exeporfinium chloride)

Catalog No.: PC-63533Not For Human Use, Lab Use Only.

XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL), including Staphylococcus aureus.

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    Biological Activity

    XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL), including Staphylococcus aureus.
    XF-73 inhibits DNA, RNA and protein synthesis and is rapidly bactericidal against S. aureus SH1000, exhibits rapid membrane-perturbing activity.

    Physicochemical Properties

    M.Wt 765.824
    Formula C44H50Cl2N6O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-Propanaminium, 3,3'-[21H,23H-porphine-5,15-diylbis(4,1-phenyleneoxy)]bis[N,N,N-trimethyl-, dichloride (9CI)

    References

    1. Ooi N, et al. J Antimicrob Chemother. 2009 Oct;64(4):735-40.

    2. Ooi N, et al. J Antimicrob Chemother. 2010 Jan;65(1):72-8.

    3. Farrell DJ, et al. Int J Antimicrob Agents. 2010 Jun;35(6):531-6.

    4. Farrell DJ, et al. Antimicrob Agents Chemother. 2011 Mar;55(3):1177-81.

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