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Chemical Structure : XMD16-5
CAS No.: 1345098-78-3
Catalog No.: PC-42339Not For Human Use, Lab Use Only.
XMD16-5 is a potent Ack1 (TNK2) inhibitor with IC50 of 0.38 uM in ELISA assay.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $158 | In stock | |
| 25 mg | $258 | In stock | |
| 50 mg | $398 | In stock | |
| 100 mg | Get quote |
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XMD16-5 is a potent Ack1 (TNK2) inhibitor with IC50 of 0.38 uM in ELISA assay.
XMD16-5 exhibits potent inhibition of growth of the TNK2 mutant expressing cell lines with IC50s of 16 nM and 77 nM for the D163E and R806Q mutations.
| M.Wt | 416.47566 | |
| Formula | C23H24N6O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 29 mg/mL |
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| Chemical Name/SMILES |
6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-11-methyl- |
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1. Miduturu CV, et al. Chem Biol. 2011 Jul 29;18(7):868-79.
2. Maxson JE, et al. Cancer Res. 2016 Jan 1;76(1):127-38.
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