Chemical Structure : Y2R antagonist SF-11
CAS No.: 443292-81-7
Catalog No.: PC-26143Not For Human Use, Lab Use Only.
Y2R antagonist SF-11 is potent, selective and brain penetrant antagonist of Neuropeptide Y Y2 Receptor (Y2R) with IC50 of 199 nM, induces antidepressant-like effect in rats.
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Y2R antagonist SF-11 is potent, selective and brain penetrant antagonist of Neuropeptide Y Y2 Receptor (Y2R) with IC50 of 199 nM, induces antidepressant-like effect in rats.
| M.Wt | 446.61 | |
| Formula | C27H30N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-(4-ethoxyphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinecarbothioamide |
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1. Domin H, et al. ACS Chem Neurosci. 2019 Aug 21;10(8):3454-3463.
2. Brothers SP, et al. Mol Pharmacol. 2010;77(1):46-57.

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