YK-I-02

Chemical Structure : YK-I-02

Catalog No.: PC-23889Not For Human Use, Lab Use Only.

YK-I-02 is a specific inhibitor of fungal casein kinase 1 (CK1) family member Yck2 with sub-micromolar potencey, 8- to 20-fold selectivity over CK1α but less than 3-fold selectivity over p38α.

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Biological Activity

YK-I-02 is a specific inhibitor of fungal casein kinase 1 (CK1) family member Yck2 with sub-micromolar potencey, 8- to 20-fold selectivity over CK1α but less than 3-fold selectivity over p38α.

Physicochemical Properties

M.Wt	314.32
Formula	C19H11FN4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine-6-carbonitrile

References

1. Shirley DJ, et al. bioRxiv [Preprint]. 2025 Jan 10:2025.01.10.632200.

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YK-I-02

Biological Activity

Physicochemical Properties

References

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