YR-290

Chemical Structure : YR-290

Catalog No.: PC-24982Not For Human Use, Lab Use Only.

YR-290 is a specific inhibitor of TGFβ receptor 1 (TGFβR1) with IC50 of 137 nM, exhibits anticancer activity of IC50 value of 9.13 μM against A549 cell.

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Biological Activity

YR-290 is a specific inhibitor of TGFβ receptor 1 (TGFβR1) with IC50 of 137 nM, exhibits anticancer activity of IC50 value of 9.13 μM against A549 cell.

Physicochemical Properties

M.Wt	290.37
Formula	C19H18N2O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-phenyl-1-(1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)ethan-1-one

References

1. Fang Y, et al. J Natl Cancer Inst. 2013 Jan 2;105(1):47-58.

2. Zhang J, et al. Eur J Med Chem. 2025 May 5;289:117442.

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YR-290

Biological Activity

Physicochemical Properties

References

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