Chemical Structure : YTX-465
CAS No.: 2225824-53-1
Catalog No.: PC-35915Not For Human Use, Lab Use Only.
YTX-465 (YTX465) is a specific small molecule that rescues yeast from a-Syn cytotoxicity with EC50 of 15 nM, via inhibiting Ole1, the yeast homolog of human stearoyl-CoA desaturase (SCD).
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YTX-465 (YTX465) is a specific small molecule that rescues yeast from a-Syn cytotoxicity with EC50 of 15 nM, via inhibiting Ole1, the yeast homolog of human stearoyl-CoA desaturase (SCD).
YTX-465 is inactive at SCD1.
M.Wt | 458.522 | |
Formula | C25H26N6O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-(2-(4-(3-(1,3-dimethyl-1H-indazol-6-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-2-oxoethyl)benzamide |
1. Vincent BM, et al. Cell Rep. 2018 Dec 4;25(10):2742-2754.e31.
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