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YW2065

Chemical Structure : YW2065

CAS No.: 2131223-85-1

YW2065

Catalog No.: PC-49509Not For Human Use, Lab Use Only.

YW2065 is is a small molecule inhibitor of Wnt signaling by stabilizing Axin-1, also activates the tumor suppressor AMPK, demonstratesexcellent anti-CRC effects in vitro and in vivo.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

YW2065 is is a small molecule inhibitor of Wnt signaling by stabilizing Axin-1, also activates the tumor suppressor AMPK, demonstratesexcellent anti-CRC effects in vitro and in vivo.

Physicochemical Properties

M.Wt 407.27
Formula C20H15BrN4O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(2-bromophenyl)-5-methyl-N-(quinolin-2-yl)-1H-pyrazole-4-carboxamide

References

1. Wei Yang, et al. J Med Chem. 2019 Dec 26;62(24):11151-11164.

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