YX-2-115 | CDK6 inhibitor | Probechem Biochemicals

Chemical Structure : YX-2-115

Catalog No.: PC-73343Not For Human Use, Lab Use Only.

YX-2-115 is a palbociclib derivative compound with piperazine-linker tail for PROTAC YX-2-107 synthesis, inhibits CDK6 with IC50 of 4.5 nM.

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Biological Activity

YX-2-115 is a palbociclib derivative compound with piperazine-linker tail for PROTAC YX-2-107 synthesis, inhibits CDK6 with IC50 of 4.5 nM.

M.Wt	547.664
Formula	C28H37N9O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-acetyl-2-((5-(4-((2-aminoethyl)glycyl)piperazin-1-yl)pyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one

1. Marco De Dominici, et al. Blood. 2020 Apr 30;135(18):1560-1573.